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Medically reviewed by Dr. David Borenstein, MD. Last reviewed November 2026.
In short: Dr. David Borenstein is a New York physician and functional medicine practitioner who has practiced in Manhattan for over 20 years. He looks for the root cause of chronic symptoms such as fatigue, thyroid problems, gut issues and hormone imbalance, using detailed history, advanced lab testing and a personalized treatment plan. His office is at 308 Fifth Avenue in Midtown Manhattan, with telemedicine available.
You’ve seen your primary care doctor. Maybe an endocrinologist, a gastroenterologist and a rheumatologist, too. Each one ran tests, told you the results were “normal,” and sent you home still exhausted, bloated, foggy or in pain.
That gap between “normal labs” and how you actually feel is where functional medicine starts.

Functional medicine is a physician-led approach that identifies and treats the underlying causes of chronic illness, rather than only managing symptoms. It treats the body as connected systems: gut, hormones, immune function, metabolism and stress response all affect each other.
Dr. Borenstein likes to quote the Institute for Functional Medicine’s principle: one condition can have many causes, and one cause can produce many conditions. Your fatigue may come from your thyroid, your gut, your sleep, or all three. His job is to find out which.
Call Manhattan Integrative Medicine at (212) 262-2412 or request a consultation.
In short: Dr. David Borenstein is a New York physician and functional medicine practitioner who has practiced in Manhattan for over 20 years. He looks for the root cause of chronic symptoms such as fatigue, thyroid problems, gut issues and hormone imbalance, using detailed history, advanced lab testing and a personalized treatment plan. His office is at 308 Fifth Avenue in Midtown Manhattan, with telemedicine available.
You’ve seen your primary care doctor. Maybe an endocrinologist, a gastroenterologist and a rheumatologist, too. Each one ran tests, told you the results were “normal,” and sent you home still exhausted, bloated, foggy or in pain.
That gap between “normal labs” and how you actually feel is where functional medicine starts.
Functional medicine is a physician-led approach that identifies and treats the underlying causes of chronic illness, rather than only managing symptoms. It treats the body as connected systems: gut, hormones, immune function, metabolism and stress response all affect each other.
Dr. Borenstein likes to quote the Institute for Functional Medicine’s principle: one condition can have many causes, and one cause can produce many conditions. Your fatigue may come from your thyroid, your gut, your sleep, or all three. His job is to find out which.
Call Manhattan Integrative Medicine at (212) 262-2412 or request a consultation.
A functional medicine doctor is a licensed physician who spends more time on each patient, orders broader testing, and connects findings across body systems that conventional care usually treats separately.
|
Conventional visit |
Functional medicine visit with Dr. Borenstein |
|
|---|---|---|
Visit time |
Often 15 minutes |
Time to review your full history, symptoms and prior labs |
Focus |
Diagnose and treat the main symptom |
Find why the symptom developed |
Lab ranges |
“Normal” reference range |
Optimal ranges, plus markers often skipped (free T3, reverse T3, antibodies) |
Treatment |
Usually one medication per problem |
Medication when needed, plus nutrition, supplements, sleep and hormone work |
Follow-up |
As needed |
Scheduled re-testing and plan adjustment |
Functional medicine does not replace conventional medicine. Dr. Borenstein is a board-certified physician who prescribes medication, orders imaging, and refers to specialists when that is the right call.
Most of Dr. Borenstein’s patients come with one of these patterns:
|
System |
Common tests |
|---|---|
Thyroid |
TSH, free T4, free T3, reverse T3, TPO and thyroglobulin antibodies |
Adrenal / stress |
Cortisol (blood or saliva rhythm), DHEA-S |
Sex hormones |
Estradiol, progesterone, total and free testosterone, SHBG; saliva or urine hormone metabolites |
Metabolic |
Fasting glucose, insulin, hemoglobin A1C, leptin, lipid panel |
Inflammation |
hs-CRP, homocysteine |
Nutrients |
Ferritin, vitamin D, vitamin B12, magnesium |
Gut |
SIBO breath test, comprehensive stool analysis |
Infections / environment |
Epstein-Barr and other viral titers, mold (mycotoxin) testing |
Not every patient needs every test. Dr. Borenstein orders what your history justifies.
Results vary by age, genetics, overall health and how closely the plan is followed.
Dr. Borenstein earned his medical degree at the Technion Faculty of Medicine in Israel and completed his internship at Staten Island University Hospital. He is board-certified in Physical Medicine and Rehabilitation, certified in Medical Acupuncture, and a member of the Institute for Functional Medicine, ACAM and A4M. He has been quoted on thyroid and hormone health by Vogue, Everyday Health and the Chicago Tribune.
Manhattan Integrative Medicine, 308 Fifth Avenue, 5th Floor, New York, NY 10001, near Herald Square and the Empire State Building. Monday–Thursday 8am–5pm, Friday 9am–5pm. Telemedicine is available. We also see patients on Fridays in Huntington, Long Island.
Functional medicine is a method: finding and treating root causes across connected body systems. Integrative medicine is a philosophy of combining conventional and complementary treatments. Dr. Borenstein practices both: he uses the functional method to diagnose and draws on conventional and complementary tools to treat.
Titles vary. Some functional medicine practitioners are chiropractors, nutritionists or health coaches. Dr. Borenstein is a licensed medical doctor (MD) in New York, board-certified in Physical Medicine and Rehabilitation, who can order any lab test and prescribe medication.
Manhattan Integrative Medicine does not accept private insurance, Medicare or Medicaid. Visits are self-pay.
It depends on the cause. Thyroid and hormone corrections often show change within 6–12 weeks; gut and chronic fatigue cases can take several months. Dr. Borenstein re-tests and adjusts along the way.
At this practice: chronic fatigue, fibromyalgia, thyroid disorders and Hashimoto’s, SIBO and digestive issues, hormone imbalance, menopause, low testosterone, weight gain, insulin resistance, mold exposure and long COVID.
Yes. Follow-ups and many initial visits can be done by video. Some patients need an in-person exam first.
No. Call (212) 262-2412 or request a consultation online.
If you’ve been told your labs are normal but you don’t feel normal, a root-cause evaluation is the next step. Call Dr. Borenstein at (212) 262-2412 or contact us here.