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Longevity Medicine Doctor in New York City, NY
Medically reviewed by Dr. David Borenstein, MD. Last reviewed November 2026.
In short: Longevity medicine is preventive, physician-led care aimed at adding healthy years to your life. Dr. David Borenstein, a Manhattan physician with over 20 years in functional and integrative medicine, runs a detailed assessment of heart, metabolic, hormone, inflammation and nutrient markers, then builds a personal plan to lower your risk of the diseases that most shorten healthy life.
You feel fine. Or mostly fine. Your annual physical is “normal.” But your father had a heart attack at 62, your energy isn’t what it was at 40, and you’d like the next 30 years to be good ones, not just long ones.
Longevity medicine focuses on healthspan: the years you live with good physical, cognitive and metabolic health. It starts before disease, when there is still the most room to change course.
Call (212) 262-2412 or request a consultation.
What does a longevity doctor do?
A longevity doctor looks for early signs of the four conditions that cause most deaths and disability in adults: heart disease, type 2 diabetes and metabolic disease, cancer, and cognitive decline. They then work to delay them. A standard physical screens for disease that is already present. A longevity evaluation measures risk years earlier, using markers a routine visit often skips.
It is not anti-aging hype. No pill has been proven to slow human aging. What works is well studied: managing blood pressure, cholesterol particles and blood sugar early; building muscle and fitness; sleeping well; and treating hormone deficiency when it’s present.
What the longevity assessment covers
Depending on your history, Dr. Borenstein’s assessment can cover five areas:
|
Area |
Markers |
Why it matters |
|---|---|---|
Heart and blood vessels |
ApoB, Lp(a), full lipid panel, blood pressure |
ApoB and Lp(a) predict heart risk better than LDL alone; Lp(a) is genetic and checked once |
Metabolic health |
Fasting glucose, fasting insulin, hemoglobin A1C, leptin, waist measurement |
Insulin resistance shows up 10+ years before diabetes |
Inflammation |
hs-CRP, homocysteine, ferritin |
Chronic inflammation drives heart disease and other age-related illness |
Hormones |
Thyroid panel with free T3 and reverse T3, estradiol, progesterone, testosterone, DHEA-S, cortisol |
Hormone decline affects muscle, bone, mood, sleep and metabolism |
Nutrients |
Vitamin D, B12, magnesium, omega-3 index |
Common deficiencies that affect energy, bone and brain |
He also reviews your family history, medications, sleep, stress, alcohol, exercise, and screenings that are due (colonoscopy, mammogram, prostate, skin, bone density), and coordinates them with your other doctors.
Your longevity plan
Results become a prioritized plan, reviewed with you in person. Depending on your results, it may include:
- Cardiometabolic risk reduction: nutrition changes, supplements where evidence supports them, and medication such as statins or blood pressure drugs when needed
- Exercise prescription: strength training to preserve muscle, plus aerobic work. As a Physical Medicine and Rehabilitation specialist, Dr. Borenstein designs this around joints and old injuries
- Hormone replacement therapy for menopause, perimenopause or low testosterone
- Thyroid optimization
- Metabolic weight loss
- Gut health work if testing shows SIBO or other dysfunction
- Sleep evaluation and treatment, including sleep apnea screening
- Regenerative treatments for joint pain that limits activity
Follow-up testing shows what’s working, and the plan is adjusted.
Who is longevity medicine for?
- Adults 35 and up who want a plan before problems start
- People with a family history of early heart disease, diabetes or dementia
- Anyone told their labs are “borderline” and to “watch it”
- Women in perimenopause or menopause
- Men noticing lower energy, muscle loss or weight gain
- Busy New Yorkers who want one physician to connect results that are scattered across specialists
About Dr. David Borenstein, MD
Dr. Borenstein has practiced root-cause, functional medicine in Manhattan for over 20 years. He is board-certified in Physical Medicine and Rehabilitation and a member of the American Academy of Anti-Aging Medicine (A4M) and the Institute for Functional Medicine. He was quoted in Vogue in 2022 on metabolism and aging.
Frequently asked questions
What is the difference between longevity medicine and functional medicine?
Functional medicine finds the root cause of symptoms you have now. Longevity medicine applies the same detailed testing to people who may feel well, to lower future disease risk. Dr. Borenstein uses both.
What tests does a longevity doctor order?
Commonly ApoB, Lp(a), fasting insulin, hemoglobin A1C, hs-CRP, a full thyroid panel, sex hormones, vitamin D and B12, plus age-appropriate cancer screening.
At what age should I start?
Most benefit starts in your 30s and 40s, when risk markers appear years before disease. It’s never too late; older adults gain a lot from strength and fall prevention work.
Is longevity medicine evidence-based?
The core of it is: blood pressure, cholesterol, blood sugar control, exercise, sleep and treating hormone deficiency are all well supported. Newer therapies marketed for aging, such as peptides and some supplements, have limited human evidence, and Dr. Borenstein says so.
Can I do this by telemedicine?
The first assessment is best in person in Manhattan. Results reviews and follow-ups can be done by video.
Reserve your longevity assessment
Call Dr. Borenstein at (212) 262-2412 or contact us here. Manhattan office at 308 Fifth Avenue, near Herald Square; Fridays in Huntington.
Serving patients across New York City: Manhattan (Midtown, NoMad, Flatiron, Chelsea, Murray Hill, Gramercy, the Upper East Side and the Upper West Side), Brooklyn, Queens, the Bronx and Staten Island, plus Long Island, Westchester and the greater New York metro area.
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